SUPPORT BUSINESSES THAT MAKE OUR MISSION POSSIBLE INTHEVUE.COM | FEBRUARY 2026 19 125 Augusta Avenue Paducah, KY 42003 Mon-Fri 8am-4pm Sat 8am-11am | Sun Closed KEEP HEARTWORM PROTECTION GOING ALL YEAR LONG—EVEN IN COOLER WEATHER. Heartworm prevention is simple, safe, and affordable. Protect your best friend all year long. Protect & save with our online pharmacy ©VUE2026 Ryan Frazine, MD, and Carla Frazine, PA-C, oversee Advanced Internal Medicine, Frazine Medical Weight Loss, and Frazine Wellness. Their partnership began long before their businesses, starting in high school at Massac County. Though college and career paths took them to different cities - Carla to physician assistant school at Saint Louis University and Ryan to medical school in Chicago - they stayed connected. They married in 2000, and by 2014, after years of experience and shared vision, they officially launched Advanced Internal Medicine together. Their partnership thrives on communication, respect, and knowing when to step away from work to focus on life and family. Ryan naturally operates in the big-picture space, envisioning strategy, long-term growth, and new opportunities. Carla is the execution expert, turning ideas into action, keeping projects moving, and making sure no detail is overlooked. Ryan provides the vision; Carla ensures it becomes reality - a combination that keeps both their businesses and partnership strong. The biggest lesson they’ve learned from each other is staying grounded in purpose. Running a medical practice can be overwhelming, but they constantly refocus on what matters most: the people they serve. This helps them block distractions, simplify decisions, and preserve fulfillment and passion in their work. Their shared goal is to grow their businesses sustainably while keeping them meaningful and enjoyable. They aim to focus on leadership, mentorship, and innovation, all while maintaining flexibility to enjoy family, relationships, and the life they’ve built together, proving that work can be both purposeful and personal. Ryan FRAZINE, MD Carla FRAZINE, PA-C & Advanced Internal Medicine, Frazine Medical Weight Loss, and Frazine Wellness
February 2026
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